Thursday, 28. August 2008


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Competence platform

This website is only filled with sample research information and serves primarily to illustrate the concept of the Competence platform. All partners to the BioCompetence Network have access to the Competence platform at www.bio-competence.com (password protected), where their research competences are thematically accessible and possible to analyse through novel tools.

If you desire more information, please contact the PR Office of the BioCompetence Network at info@biocompetence.org.

88 Projects relatiert zu Competence platform
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Modulation of Proteolysis in Tumor Cells (Maria G. Masucci)
Using a panel of LCLs EBV carrying BL lines and pairs of BL/LCL-like cells of the same genetic background we have found that BL cells are resistant to the induction of apoptosis and fail to accumulate » more





Gene Inactivation Test (GIT) project (Eugene Zabarovsky)
Evidence of the ability to suppress cellular proliferation cannot always be used for the identification of a tumor suppressor. In many tumors carrying multiple genetic alterations, reconstituting a » more





Slalom libraries: a new approach for simultaneous mapping and sequencing (Eugene Zabarovsky)
Our aim is to develop techniques to allow qualititative and quantitative analysis of complex microbial systems, such as the normal flora of the gut. For this purpose we will adapt and develop new » more





Bacterial ecology and epidemiology (Roland Möllby)
The project is aimed at developing methods for typing of bacteria and bacterial communities, and to use the achieved knowledge for ecological and epidemiological studies of bacteria and bacterial » more





Persistent infections (Mikael Rhen)
Our macrophage-adapted mutants tend not to be more virulent in mouse infection models, but selected mutants show altered infection pathogenesis. One such mutant is defective in its polynucleotide » more





Snake venom toxins (Monica Thelestam)
Effect of tissue-damaging toxins from the venom of the snake Bothrops asper on infection of muscle tissue by Staphylococcus aureus » more





Bacterial recognition by epithelial cells (Agneta Richter-Dahlfors)
Upon recognition of conserved molecular microbial patterns (e.g. LPS and cell wall components) Toll-like ... » more





Pseudomonas aeruginosa: Large chromosomal inversions (Ute Römling)
Large chromosomal inversions occur in the genomes of all species, but become commonly not fixed in the chromosome. However, the chromosomes of closely related species or subspecies can be usually » more





Bacterial virulence factors and relations to the host response (Roland Möllby)
The group investigates occurrence of bacterial virulence factors and relations between them and the host response. We investigate Escherichia coli urinary tract infections and their immune response » more





Has the number of tumor antagonizing genes been underestimated? (Georg Klein)
Ever since the early 50s, my and my collaborators? research work has resolved around multistep carcinogenesis. In the early 50s, we have been among the first to document the role of Darwinian » more

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